《Profiling structural diversity and activity of 2-alkyl-4(1H)-quinolone N-oxides of Pseudomonas and Burkholderia》 was published in Chemical Communications (Cambridge, United Kingdom) in 2020. These research results belong to Szamosvari, David; Prothiwa, Michaela; Dieterich, Cora Lisbeth; Boettcher, Thomas. Reference of Ethyl 2-methyl-3-oxobutanoate The article mentions the following:
We synthesized all major saturated and unsaturated 2-alkyl-4(1H)-quinolone N-oxides of Pseudomonas and Burkholderia, quantified their native production levels and characterized their antibiotic activities against competing Staphylococcus aureus. We demonstrate that quinolone core methylation and position of unsaturation in the alkyl-chain dictate antibiotic potency which supports the proposed mechanism of action. In addition to this study using Ethyl 2-methyl-3-oxobutanoate, there are many other studies that have used Ethyl 2-methyl-3-oxobutanoate(cas: 609-14-3Reference of Ethyl 2-methyl-3-oxobutanoate) was used in this study.
Ethyl 2-methyl-3-oxobutanoate(cas: 609-14-3) belongs to ketone compounds. Ketones are highly reactive, although less so than aldehydes, to which they are closely related. Much of their chemical activity results from the nature of the carbonyl group. Ketones readily undergo a wide variety of chemical reactions.Reference of Ethyl 2-methyl-3-oxobutanoate
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