Sun, Zhian; Liu, Huachun; Zhou, Yanqiang; Zhao, Shanwen; Li, Jianmin; Wang, Xiaoxiao; Gong, Bolin published the artcile< A restricted access molecularly imprinted polymer coating on metal-organic frameworks for solid-phase extraction of ofloxacin and enrofloxacin from bovine serum>, Electric Literature of 3290-92-4, the main research area is ofloxacin enrofloxacin serum solid phase extraction metal organic framework.
A restricted access molecularly imprinted polymer (RAMIP) crosslinked with bovine serum albumin (BSA) was prepared on the surface of the mesoporous UiO-66-NH2 metal-organic framework (MOF). The surface morphol., imprinting behavior, and protein exclusion properties of UiO-66-NH2@RAMIP@BSA were investigated. The maximum adsorption capacity was 50.55 mg g-1 for ofloxacin, with a 99.4% protein exclusion rate. Adsorption equilibrium was reached in 9 min. Combined with RP-HPLC, a solid-phase extraction column filled with UiO-66-NH2@RAMIP@BSA was used to selectively enrich and analyze ofloxacin and enrofloxacin antibiotics from bovine serum with recoveries of 93.7-104.2% with relative standard deviations of 2.0-4.5% (n = 3). The linear range and the limit of detection were 0.1-100μg mL-1 and 15.6 ng mL-1, resp. These results suggest that UiO-66-NH2@RAMIP@BSA is an efficient pretreatment adsorbent for biol. sample anal.
RSC Advances published new progress about Adsorption. 3290-92-4 belongs to class esters-buliding-blocks, and the molecular formula is C18H26O6, Electric Literature of 3290-92-4.
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics