In 2013,Schofield, Joseph; Brasseur, Denis; Bruin, Beatrice; Vassal, Thierry; Klieber, Sylvie; Arabeyre, Catherine; Bourrie, Martine; Sadoun, Freddy; Fabre, Gerard published 《Effect of deuteration on the metabolism and clearance of some pharmacologically active compounds-synthesis and in vitro metabolism of deuterated derivatives of dronedarone》.Journal of Labelled Compounds and Radiopharmaceuticals published the findings.Recommanded Product: 6149-41-3 The information in the text is summarized as follows:
The synthesis and in vitro metabolism studies of a family of specifically deuterated derivatives of dronedarone (I) are described. Metabolic stability and clearance of the parent compound are not sensitive to deuterium substitution, irresp. of the position of the heavy label. The results came from multiple reactions, including the reaction of Methyl 3-hydroxypropanoate(cas: 6149-41-3Recommanded Product: 6149-41-3)
Methyl 3-hydroxypropanoate(cas: 6149-41-3) belongs to esters with low molecular weight are commonly used as fragrances and found in essential oils and pheromones. Their flexibility and low polarity is manifested in their physical properties; they tend to be less rigid (lower melting point) and more volatile (lower boiling point) than the corresponding amides. Recommanded Product: 6149-41-3
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics