Mattingly, Stephanie J.; Wuest, Frank; Schirrmacher, Ralf published the artcile< Synthesis of 2-Fluoroacetoacetic Acid and 4-Fluoro-3-hydroxybutyric Acid>, Formula: C6H10O5, the main research area is fluoroacetoacetic acid preparation; acetoacetate ester fluorination; fluoro hydroxybutyric acid preparation; epoxyester fluorination.
The synthesis of two new fluorinated butyric acids (and three related esters) these were derivatives of the metabolites acetoacetic acid and 3-hydroxybutyric acid. 4-Fluoro-3-hydroxybutyric acid was synthesized from epoxy ester precursors via ring opening by triethylamine trihydrofluoride. 2-Fluoroacetoacetic acid was prepared by electrophilic fluorination of an acid-labile β-keto ester. The gradual pH-dependent decarboxylation of 2-fluoroacetoacetic acid was investigated by 19F NMR spectroscopy.
Synthesis published new progress about Acid halides Role: SPN (Synthetic Preparation), PREP (Preparation). 617-55-0 belongs to class esters-buliding-blocks, and the molecular formula is C6H10O5, Formula: C6H10O5.
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics