Matos, Jeishla L. M.; Vasquez-Cespedes, Suhelen; Gu, Jieyu; Oguma, Takuya; Shenvi, Ryan A. published their research in Journal of the American Chemical Society on December 12 ,2018. The article was titled 《Branch-Selective Addition of Unactivated Olefins into Imines and Aldehydes》.Name: Ethyl (2S)-2-amino-3,3-dimethylbutanoate The article contains the following contents:
Radical hydrofunctionalization occurs with ease using metal-hydride hydrogen atom transfer (MHAT) catalysis to couple alkenes and competent radicalophilic electrophiles. Traditional two-electron electrophiles have remained unreactive. Herein we report the reductive coupling of electronically unbiased olefins with imines and aldehydes. Iron catalysis allows addition of alkyl-substituted olefins into imines through the intermediacy of free radicals, whereas a combination of catalytic Co(Salt-Bu,t-Bu) and chromium salts enables a branch-selective coupling of olefins and aldehydes through the formation of a putative alkyl chromium intermediate. The results came from multiple reactions, including the reaction of Ethyl (2S)-2-amino-3,3-dimethylbutanoate(cas: 69557-34-2Name: Ethyl (2S)-2-amino-3,3-dimethylbutanoate)
Ethyl (2S)-2-amino-3,3-dimethylbutanoate(cas: 69557-34-2) belongs to esters. Esters are more polar than ethers but less polar than alcohols. Name: Ethyl (2S)-2-amino-3,3-dimethylbutanoate They participate in hydrogen bonds as hydrogen-bond acceptors, but cannot act as hydrogen-bond donors, unlike their parent alcohols.
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics