COA of Formula: C12H15ClN2O2In 2021 ,《A fast and direct iodide-catalyzed oxidative 2-selenylation of tryptophan》 was published in Chemical Communications (Cambridge, United Kingdom). The article was written by Gao, Yu-Ting; Liu, Shao-Dong; Cheng, Liang; Liu, Li. The article contains the following contents:
A metal-free 2-selenylation of tryptophan derivatives is reported, where the use of iodide as the catalyst and oxone as the oxidant is key to obtain high yields. Various functional groups within the di-selenyl and the indole ring are tolerated, and no racemization is generally observed In the experiment, the researchers used many compounds, for example, H-Trp-OMe.HCl(cas: 7524-52-9COA of Formula: C12H15ClN2O2)
H-Trp-OMe.HCl(cas:7524-52-9) is one of amino acid derivatives. Amino acid derivatives represent an important category of skin penetration promoters. These compounds possess hydrophobic chains attached to an amino acid headgroup via a biodegradable ester bond. Due to the amphiphilic nature of these derivatives, it is possible for them to enter into the SC lipid barrier and significantly disorganize skin membrane lipids.COA of Formula: C12H15ClN2O2
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