Yang, Jianjing; Zeng, Ting; Yan, Kelu; Qin, Zonghui; Wen, Jiangwei published the artcile< Direct Synthesis of Alkylthioimidazoles: One-Pot Three-Component Cross-Coupling Mediated by Paired Electrolysis>, Synthetic Route of 19241-24-8, the main research area is isothiocyanate cyanoacetate haloalkane electrochem multicomponent cross coupling; alkylthioimidazole preparation.
The direct synthesis of alkylthioimidazoles was initially accomplished via a one-pot three-component cross-coupling mediated by a paired electrolysis strategy using non-activated chloroalkane as the alkylating agent. This protocol provides a straightforward method for the preparation of alkylthioimidazoles by employing water as the co-solvent at room temperature without any exogenous-oxidants and metal catalysts. Inactivated primary, secondary, tertiary haloalkanes and various isothiocyanates was compatible with the established conditions to obtain the corresponding products with a moderate yield. The mechanism of this one-pot three-component cross-coupling reaction undergoes a radical process mediated by paired electrolysis.
Advanced Synthesis & Catalysis published new progress about Acetates Role: RCT (Reactant), RACT (Reactant or Reagent). 19241-24-8 belongs to class esters-buliding-blocks, and the molecular formula is C11H13NS, Synthetic Route of 19241-24-8.
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics