Papageorgiou, Christos; Benezra, Claude published the artcile< Use of enzymic hydrolysis of dimethyl malates for a short synthesis of tulipalin B and of its enantiomer>, Safety of (S)-Dimethyl 2-hydroxysuccinate, the main research area is dimethyl malate regiochem esterase hydrolysis; tulipalin B.
Pig liver esterase hydrolyzes the ester function α to the hydroxyl group in di-Me malate. This regiospecific reaction was used to synthesize (+)- and (-)-tulipalin B.
Journal of Organic Chemistry published new progress about Regiochemistry. 617-55-0 belongs to class esters-buliding-blocks, and the molecular formula is C6H10O5, Safety of (S)-Dimethyl 2-hydroxysuccinate.
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics