《The first tryptophan based turn-off chemosensor for Fe2+ ion detection》 was written by Nagarajan, Rajendran; Vanjare, Balasaheb D.; Hwan Lee, Ki. COA of Formula: C12H15ClN2O2This research focused ontryptophan fluorescent chemosensor iron ion detection; Chemosensor; Fe(2+) ion sensor; Fluorescence quenching; Metal ions; PET mechanism; Tryptophan. The article conveys some information:
In this research work, we have designed and synthesized a novel Tryptophan-Quinoline conjugated turn-off chemosensor 4 (I) for the selective detection of Fe2+ ion with high sensitivity (3.06μM) among 21 metal cations such as Ag+, Ca+, Cs+, Cu+, K+, Na+, NH+4, Ba2+, Ca2+, Cd2+, Co2+, Cu2+, Mn2+, Ni2+, Pb2+, Zn2+, Al3+, Au3+, Cr3+ and Fe3+ in DMF-HEPES (1 mM, pH = 7.0, 1:1, volume/volume) aqueous-organic solvent system. It showed a fluorescence quenching mechanism through the blocked PET process. The optical properties, binding mode of the metal ion with the receptor, plausible electron transfer mechanism, and its practical applications have been discussed. This work will open up a new avenue in amino acid-based Fe2+ ion sensors. The results came from multiple reactions, including the reaction of H-Trp-OMe.HCl(cas: 7524-52-9COA of Formula: C12H15ClN2O2)
H-Trp-OMe.HCl(cas:7524-52-9) is one of amino acid derivatives. Amino acid derivatives represent an important category of skin penetration promoters. These compounds possess hydrophobic chains attached to an amino acid headgroup via a biodegradable ester bond. Due to the amphiphilic nature of these derivatives, it is possible for them to enter into the SC lipid barrier and significantly disorganize skin membrane lipids.COA of Formula: C12H15ClN2O2
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