Category: esters-buliding-blocksIn 2021 ,《Identification of Novel Simulants for Toxic Industrial Chemicals and Chemical Warfare Agents for Human Decontamination Studies: A Systematic Review and Categorisation of Physicochemical Characteristics》 appeared in International Journal of Environmental Research and Public Health. The author of the article were James, Thomas; Collins, Samuel; Marczylo, Tim. The article conveys some information:
A review. Chem. simulants have long been used in human trials of mass decontamination to determine the efficacy of decontamination interventions against more toxic agents. Until now, reliance has mostly been on individual chems. as surrogates to specific agents (e.g., Me salicylate for sulfur mustard). A literature review was conducted to identify chems. that had been previously tested on human volunteers and that represent diverse physicochem. characteristics in order to create a repository for chem. simulants. Of the 171 unique chems. identified, 78 were discounted for the risk they could pose to human volunteers, 39 were deemed suitable for use, and a further 54 were considered to be possible simulants but would require further research. Suitable simulants included both solid and liquid chems. spanning a wide range of physicochem. properties including mol. weight, octanol/water partition coefficient, vapor pressure, and solubility This review identifies an array of potential simulants suitable for use in human volunteer decontamination studies and is of relevance to future studies on systemic absorption and surface decontamination. After reading the article, we found that the author used Methyl Salicylate(cas: 119-36-8Category: esters-buliding-blocks)
Methyl Salicylate(cas: 119-36-8) is a natural herbivore-induced plant volatile. It is a naturally occurring product in trees, legumes, exotic plants, vegetables, berries, and the primary constituent of the oil of wintergreen.Methyl Salicylate is produced from salicylic acid.Category: esters-buliding-blocks
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics