《Synthesis of N-methyl-1H-indole and adamantane fragment containing derivatives via UGI-4CR》 was published in Research Journal of Pharmaceutical, Biological and Chemical Sciences in 2019. These research results belong to Bukia, Tinatin; Tevzadze, Tekle; Maisuradze, Jimsher; Samsonyia, Shota. Formula: C10H14ClNO2 The article mentions the following:
An efficient synthesis of N-Methyl-1H-indole and adamantane containing dipeptides obtained via Ugi-four component reaction (U4-CR) by the interaction of an amine, aldehyde, N-methyl-1H-indole-2-carboxylic acid and adamantyl-1-isonitrile was described. U4-CR involved a one-pot condensation of an amine, a carbonyl compound, a carboxylic acid, and an isocyanide to provide a substituted peptide-like product. For N-methyl-1H-indole and adamantane containing dipeptides were established the feasibility of the strategy and was optimized the reaction conditions including temperature, solvents and the influence of bases. The results came from multiple reactions, including the reaction of H-Phg-OEt.HCl(cas: 59410-82-1Formula: C10H14ClNO2)
H-Phg-OEt.HCl(cas: 59410-82-1) belongs to esters. Esters are more polar than ethers but less polar than alcohols. Formula: C10H14ClNO2 They participate in hydrogen bonds as hydrogen-bond acceptors, but cannot act as hydrogen-bond donors, unlike their parent alcohols.
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics