Plazek, E.; Rodewald, Z. published the artcile< The iodination of 2-picoline>, Recommanded Product: (9Z,12Z)-Methyl octadeca-9,12-dienoate, the main research area is .
2-Picoline (20 g.), 100 g. 50% oleum, and 60 g. iodine, on heating 6 hrs. at 200°, addition of 100 g. 50% oleum, addnl. heating (4 hrs., 210°), pouring the mixture into 400 cc. H2O, treatment with Na2CO3 until alk., and steam-distillation, yielded 5-iodo-2-methylpyridine (I), b. 205-15°, b18 105-6°; picrate m. 150°. I (5 g.), on boiling 5 hrs. with 10 g. KMnO4 in 450 cc. H2O, extraction of the unreacted I with Et2O, filtration of the MnO2, and acidification of the filtrate with H2SO4, gave 5-iodopicolinic acid, m. 204°. The acid heated slightly above its m.p. gives 3-iodopyridine, m. 52°; picrate m. 154°. I (5 g.), on heating 20 hrs. at 130-5° with 10 cc. concentrated NH4OH and 0.5 g. CuSO4, and extraction of the mixture with Et2O, gives, on removal of the Et2O, 2-methyl-5-aminopyridine, m. 92-5° (on crystallization from C6H6, the m.p. rises to 97-8°); picrate m. 203°.
Roczniki Chemii published new progress about Iodination. 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, Recommanded Product: (9Z,12Z)-Methyl octadeca-9,12-dienoate.
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics