Palo-Nieto, Carlos; Sau, Abhijit; Williams, Ryan; Galan, M. Carmen published the artcile< Cooperative Bronsted Acid-Type Organocatalysis for the Stereoselective Synthesis of Deoxyglycosides>, Synthetic Route of 4098-06-0, the main research area is deoxyglycoside oligosaccharide stereoselective synthesis; Bronsted acid organocatalysis thiourea amplification glycal glycosylation.
A practical approach for the α-stereoselective synthesis of deoxyglycosides using cooperative Bronsted acid-type organocatalysis has been developed. The method is tolerant of a wide range of glycoside donors and acceptors, and its versatility is exempedilified in the one-pot synthesis of a trisaccharide. Mechanistic studies suggest that thiourea-induced acid amplification of the chiral acid via H-bonding is key for the enhancement in reaction rate and yield, while stereocontrol is dependent on the chirality of the acid. Thiourea-induced acid amplification.
Journal of Organic Chemistry published new progress about Bronsted acids Role: CAT (Catalyst Use), USES (Uses). 4098-06-0 belongs to class esters-buliding-blocks, and the molecular formula is C12H16O7, Synthetic Route of 4098-06-0.
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics