Molchanov, A. P.;Kostikov, R. R. published 《Synthesis of dispiro[2.1.3.1]nonane and trispiro[2.1.1.37.15.13]-dodecane》 in 2012. The article was appeared in 《Russian Journal of Organic Chemistry》. They have made some progress in their research.Reference of Diethyl cyclobutane-1,1-dicarboxylate The article mentions the following:
The synthesis of dispiro[2.1.3.1]nonane and trispiro[2.1.1.37.15.13]-dodecane from di-Et cyclobutane-1,1-dicarboxylate is presented. Unique to the spirocyclic hydrocarbons of three, and/or four membered rings are high strain energy and enhanced reactivity which have versatile benefits in organic synthesis. To complete the study, the researchers used Diethyl cyclobutane-1,1-dicarboxylate (cas: 3779-29-1) .
Diethyl cyclobutane-1,1-dicarboxylate (cas:3779-29-1
) is a solid catalyst that can be used in the synthesis of alkylating agents. It is used in the manufacture of cyclopropyl ketones and has been shown to exhibit anticancer properties.
Reference:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics