Hu, Yunfei; Chen, Li; Zou, Canlin; He, Jiangtao; Feng, Luanqi; Wu, Jia-Qiang; Chen, Wen-Hua; Hu, Jinhui published the artcile< Access to 3-Amino-[1,2,4]-triazolo Pyridines and Related Heterocycles via Electrochemically Induced Desulfurative Cyclization>, Application In Synthesis of 19241-24-8, the main research area is hydrazinopyridine isothiocyanate tetrabutylammonium iodide catalyst desulfurative cyclization; amino triazolo pyridine electrochem preparation.
An efficient, one-pot approach was established for synthesizing a wide range of 3-amino-[1,2,4]-triazolo pyridines and related heterocycles from the electrochem. induced desulfurative cyclization of 2-hydrazinopyridines with isothiocyanates. The protocol allowed for the formation of C-N bonds under simple conditions without transition metals or external oxidants. The practicability of this strategy was demonstrated by its broad substrate scope, good functional group compatibility, and gram-scale synthesis. The late-stage modification of 3-amino-[1,2,4]-triazolo pyridines enabled to obtain several mols. with potent anticancer activity.
Organic Letters published new progress about Antitumor agents. 19241-24-8 belongs to class esters-buliding-blocks, and the molecular formula is C11H13NS, Application In Synthesis of 19241-24-8.
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics