Baltina, Lidia; Sapozhnikova, Tatyana; Makara, Nina; Gabdrakhmanova, Svetlana; Baltina, Lia; Kondratenko, Rimma published the artcile< Paeoniflorin benzoates: synthesis and influence on learning and memory of aged rats in the passive avoidance task>, Application In Synthesis of 112-63-0, the main research area is paeoniflorin benzoate preparation learning memory age Alzheimer’s; Paeoniflorin; benzoates; passive avoidance task; rats.
Paeoniflorin per-O-benzoates with the preserved pinane structure and rearranged aglycon , containing C4 = O function, were obtained and their influence on learning and memory of aged rats was studied in the passive avoidance task. It was found that the chem. modification of paeoniflorin affected the cognitive functions of aged rats. The introduction of C4 = O function into the pinane part of benzoate led to the improvement in learning process and preservation of the memory trace in aged rats as compared to the natural glycoside. This compound can be considered as the promising for further studies on in vivo models of disorders characteristic for Alzheimer’s disease.
Natural Product Research published new progress about Aging, animal. 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, Application In Synthesis of 112-63-0.
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics