Month: September 2022

Application In Synthesis of 1-Phenylethyl acetate《Tropolonate Salts as Acyl-Transfer Catalysts under Thermal and Photochemical Conditions: Reaction Scope and Mechanistic Insights》 was published in 2020. The authors were Lyons, Demelza J. M.;Empel, Claire;Pace, Domenic P.;Dinh, An H.;Mai, Binh Khanh;Koenigs, Rene M.;Nguyen, Thanh Vinh, and the article was included in《ACS Catalysis》. The author mentioned the following in the article:

Acyl-transfer catalysis is a frequently used tool to promote the formation of carboxylic acid derivatives, which are important synthetic precursors and target compounds in organic synthesis. However, there have been only a few structural motifs known to efficiently catalyze the acyl-transfer reaction. Herein, we introduce a different acyl-transfer catalytic paradigm based on the tropolone framework. We show that tropolonate salts, due to their strong nucleophilicity and photochem. activity, can promote the coupling reaction between alcs. and carboxylic acid anhydrides or chlorides to give products under thermal or blue light photochem. conditions. Kinetic studies and d. functional theory calculations suggest interesting mechanistic insights for reactions promoted by this acyl-transfer catalytic system. And 1-Phenylethyl acetate (cas: 93-92-5) was used in the research process.

1-Phenylethyl acetate(cas:93-92-5) is a carboxylic ester. Application In Synthesis of 1-Phenylethyl acetate It may be prepared by acetylation of methyl phenyl carbinol; from benzaldehyde by reacting with magnesium methyl bromide and subsequent acetylation; from 1-bromoethylbenzene and silver acetate in acetic acid.

Reference:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Product Details of 124-06-1《Combined application of high-throughput sequencing and UHPLC-Q/TOF-MS-based metabolomics in the evaluation of microorganisms and metabolites of dry-cured ham of different origins》 was published in 2021. The authors were Zhu, Yingying;Guo, Yun;Yang, Fenghong;Zhou, Changyu;Tang, Changbo;Zhou, Guanghong, and the article was included in《International Journal of Food Microbiology》. The author mentioned the following in the article:

Ham fermentation relies on environmental and indigenous microorganisms forming a rich microbiome, which is pivotal to taste and flavor formation. Previous studies have focused on the appearance of differences of microorganisms and metabolites, this study aims to establish the relationship between microorganisms and metabolites over a period of two years in the fermentation of hams from Jinghua (JH2), Xuanwei (XW2), Rugao (RG2), Iberian (IB2) and Parma (PA2). We profiled bacterial communities by sequencing the V3-V4 region of the 16S rRNA genes and metabolites were analyzed using LC-Q-TOF-MS. LefSe anal. showed that different biomarkers in five ham groups. OPLS anal. showed that most differential metabolites are amino acids and were associated with four metabolic pathways. Correlation anal. implies a firm pos. relationship between microorganisms and metabolites. This study provides novel insights into the taste and flavor quality of dry-cured hams of different origins due to fermentation All sequence data have been deposited in the NCBI Sequence Read Archive under accession code PRJNA728825. And Ethyl tetradecanoate (cas: 124-06-1) was used in the research process.

Ethyl tetradecanoate(cas: 124-06-1) is a natural product found in Psidium guajava, Litchi chinensis, and other organisms.Product Details of 124-06-1Ethyl myristate is a long-chain fatty acid ethyl ester resulting from the formal condensation of the carboxy group of myristic acid with the hydroxy group of ethanol.

Reference:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Li, Min;Zhang, Pan;Chen, Changle published 《Light-Controlled Switchable Ring Opening Polymerization》 in 2019. The article was appeared in 《Macromolecules (Washington, DC, United States)》. They have made some progress in their research.Reference of Oxacyclohexadecan-2-one The article mentions the following:

Salicylaldimine Zn(II) complexes bearing azobenzene moieties were prepared and characterized. Isomerization between the trans and cis forms of these complexes was achieved by exposure to light; both isomers were active in ring-opening polymerizations of ε-caprolactone (CL), rac-lactide, trimethylene carbonate, β-oxetanone, δ-valerolactone, cyclopentadecanolide, and 5-methyl-5-propyl-1,3-dioxan-2-one but exhibited different kinetic profiles. A 6-fold reactivity difference was realized for the ring-opening polymerization of CL upon irradiation with light. The light-induced isomerization also led to reactivity discrimination between different monomers in copolymerization reactions. Reversible photoswitching between two catalytically active states provides a strategy for the control of polymerization processes, as well as the compositions of the polymers produced. The experimental procedure involved many compounds, such as Oxacyclohexadecan-2-one (cas: 106-02-5) .

Oxacyclohexadecan-2-one(cas:106-02-5) is a monomer used to make PGA-co-pentadecalactone polymers to be used in the development of directly compressed prolonged release tablets of slightly soluble drugs such as ketoprofen.Reference of Oxacyclohexadecan-2-oneIt may be used for the synthesis of poly(pentadecanolide) (PPDL) by Novozyme 435 catalyzed ring-opening polymerization.

Reference:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Quality Control of 1-Phenylethyl acetateIn 2017, Yu, Wei;Zhou, Minghong;Wang, Tianqi;He, Zidong;Shi, Buyin;Xu, Yang;Huang, Kun published 《”Click Chemistry” Mediated Functional Microporous Organic Nanotube Networks for Heterogeneous Catalysis》. 《Organic Letters》published the findings. The article contains the following contents:

Azide-functionalized microporous organic nanotube networks (MONN) were prepared from graft copolymers of glycidyl methacrylate, DL-lactide, styrene, 4-(chloromethyl)styrene, and an isobutyric acid α-trithiocarbonate by Friedel-Crafts crosslinking with formaldehyde di-Me acetal followed by substitution with NaN₃. 1,3-Dipolar cycloadditions of propargyl-substituted TEMPO and DMAP with the azide-functionalized MONN yielded MONN-bound TEMPO and DMAP. MONN-bound TEMPO and MONN-bound DMAP were recyclable catalysts for the chemoselective oxidation of alcs. to aldehydes and ketones and for the acetylation of alcs. with acetic anhydride to yield acetates, resp.; the TEMPO MONN was recycled ten times with no loss in yield and fourteen times with some (10-15%) decrease in yield.1-Phenylethyl acetate (cas: 93-92-5) were involved in the experimental procedure.

1-Phenylethyl acetate(cas:93-92-5) is a carboxylic ester. Quality Control of 1-Phenylethyl acetate It may be prepared by acetylation of methyl phenyl carbinol; from 1-bromoethylbenzene and silver acetate in acetic acid; from benzaldehyde by reacting with magnesium methyl bromide and subsequent acetylation.

Reference:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Nie, Qixing;Hu, Jielun;Chen, Haihong;Geng, Fang;Nie, Shaoping published 《Arabinoxylan ameliorates type 2 diabetes by regulating the gut microbiota and metabolites》. The research results were published in《Food Chemistry》 in 2022.Application of 124-06-1 The article conveys some information:

Type 2 diabetes (T2D) is a metabolic disease characterized by hyperglycemia. Intake of dietary fiber is inversely associated with risks of T2D. Here, metabolomics and 16S rRNA gene sequencing were employed to investigate the effects of arabinoxylan on gut microbiota and their metabolites in type 2 diabetic rats. T2D increased the abundance of opportunistic pathogens (such as Desulfovibrio and Klebsiella) and the levels of 12α-hydroxylated bile acids and acylcarnitines (C3) in diabetic rats, which eventually contribute to insulin resistance and hyperglycemia. Supplementation with arabinoxylan promoted the growth of fiber-degrading bacteria to increase short-chain fatty acids (SCFAs), as well as decreased the abundance of opportunistic pathogens. Arabinoxylan treatment also decreased the concentrations of 12α-hydroxylated bile acids, and increased the levels of equol, indolepropionate, and eicosadienoic acid. This study indicated that the beneficial effects of arabinoxylan on T2D may be partially attributed to the modification of gut microbiota and related metabolites.Ethyl tetradecanoate (cas: 124-06-1) were involved in the experimental procedure.

Ethyl tetradecanoate(cas: 124-06-1) is a natural product found in Psidium guajava, Litchi chinensis, and other organisms.Application of 124-06-1Ethyl myristate is a long-chain fatty acid ethyl ester resulting from the formal condensation of the carboxy group of myristic acid with the hydroxy group of ethanol.

Reference:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Pyser, Joshua B.;Baker Dockrey, Summer A.;Benitez, Attabey Rodriguez;Joyce, Leo A.;Wiscons, Ren A.;Smith, Janet L.;Narayan, Alison R. H. published 《Stereodivergent, Chemoenzymatic Synthesis of Azaphilone Natural Products》 in 2019. The article was appeared in 《Journal of the American Chemical Society》. They have made some progress in their research.Reference of Methyl 2,4-dihydroxy-3,6-dimethylbenzoate The article mentions the following:

Selective access to a targeted isomer is often critical in the synthesis of biol. active mols. Whereas small-mol. reagents and catalysts often act with anticipated site- and stereoselectivity, this predictability does not extend to enzymes. Further, the lack of access to catalysts that provide complementary selectivity creates a challenge in the application of biocatalysis in synthesis. Here, we report an approach for accessing biocatalysts with complementary selectivity that is orthogonal to protein engineering. Through the use of a sequence similarity network (SSN), a number of sequences were selected, and the corresponding biocatalysts were evaluated for reactivity and selectivity. With a number of biocatalysts identified that operate with complementary site- and stereoselectivity, these catalysts were employed in the stereodivergent, chemoenzymic synthesis of azaphilone natural products. Specifically, the first syntheses of trichoflectin, deflectin-1a, and lunatoic acid A were achieved. In addition, chemoenzymic syntheses of these azaphilones supplied enantioenriched material for reassignment of the absolute configuration of trichoflectin and deflectin-1a based on optical rotation, CD spectra, and X-ray crystallog. To complete the study, the researchers used Methyl 2,4-dihydroxy-3,6-dimethylbenzoate (cas: 4707-47-5) .

Methyl 2,4-dihydroxy-3,6-dimethylbenzoate(4707-47-5) is used in biological study as role of androgens in inducing distinct response of epithelial-mesenchymal transition factors in human prostate cancer cells.Reference of Methyl 2,4-dihydroxy-3,6-dimethylbenzoate

Reference:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Computed Properties of C15H28O2In 2021, Demir Kanbur, Esra;Yuksek, Turan;Atamov, Vagif;Ozcelik, Ali Erdem published 《A comparison of the physicochemical properties of chestnut and highland honey: The case of Senoz Valley in the Rize province of Turkey》. 《Food Chemistry》published the findings. The article contains the following contents:

The aim of this study was to determine the physicochem. parameter changes, aroma, melissopalynol. properties, and heavy metal content of honey produced from different types of flora (chestnut and highland) in the Senoz Valley. For this purpose, the distribution of beehives at different elevation levels in the research area was determined by a layered random sampling method. Some characteristics of the honey samples were analyzed by standard laboratory methods. The highest average color (L and b) and the glucose, sucrose, Brix, Cd, Pb, Ni, Zn, and Cr values were found in the highland honeys; the highest color (a) and fructose, F/G ratio, proline, pH, conductivity, Fe, Cu, Al, and Mn values were found in the chestnut honeys. The difference between highland and chestnut honeys was statistically significant in terms of color (L and a), F/G ratio, proline, pH, elec. conductivity, Pb, Cu, and Mn. A total of 146 aromatic components were isolated in the chestnut and highland honeys.Oxacyclohexadecan-2-one (cas: 106-02-5) were involved in the experimental procedure.

Oxacyclohexadecan-2-one(cas:106-02-5) is a monomer used to make PGA-co-pentadecalactone polymers to be used in the development of directly compressed prolonged release tablets of slightly soluble drugs such as ketoprofen.Computed Properties of C15H28O2It may be used for the synthesis of poly(pentadecanolide) (PPDL) by Novozyme 435 catalyzed ring-opening polymerization.

Reference:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

HPLC of Formula: 124-06-1《Molecular mechanism of high pressure shear grinding on Feng-flavour Chinese Baijiu ageing》 was published in 2022. The authors were Jia, Wei;Fan, Zibian;Du, An;Shi, Lin, and the article was included in《Food Research International》. The author mentioned the following in the article:

Ultrahigh-pressure homogenization is a powerful technique for accelerating Baijiu ageing. In this study, the mol. mechanism of artificial ageing was thoroughly investigated utilizing foodomics combined with a mass spectrum information optimization program. Various characterizations of compounds in the ageing process were performed through ultra high performance liquid chromatog. quadrupole-orbitrap high resolution mass spectrometry (UHPLC-Q-Orbitrap) based colloid theoretics. High-pressure shear grinding provides a high-pressure and high-temperature environment for Baijiu, accelerating the formation of flavor compounds and the decomposition of odor and harmful substances, thus improving the sensory characteristics of Feng-flavor Baijiu and shortening the ageing time. A total of 2069 substances were identified according to fragment spectra and Bayesian network model-based peak distribution. Mols. with VIP > 1, including 14 esters, 10 acids, 4 ketones, 3 aldehydes, 2 alcs. and 2 phenols, were quantified as potential markers of chemometric anal. A novel prediction model for Baijiu ageing degree was furnished, and ageing years of Feng-flavor Chinese Baijiu were accurately predicted by factor anal. with KMO 0.784 and a polynomial regression model with r 0.94. The results demonstrated that in 400 bar, fresh distilled Baijiu could reach a natural ageing effect of 6.43 years, which was consistent with the sensory evaluation. And Ethyl tetradecanoate (cas: 124-06-1) was used in the research process.

Ethyl tetradecanoate(cas: 124-06-1) is a natural product found in Psidium guajava, Litchi chinensis, and other organisms.HPLC of Formula: 124-06-1Ethyl myristate is a long-chain fatty acid ethyl ester resulting from the formal condensation of the carboxy group of myristic acid with the hydroxy group of ethanol.

Reference:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Ari, Ferda;Ulukaya, Engin;Oran, Seyhan;Celikler, Serap;Ozturk, Sule;Ozel, Mustafa Zafer published 《Promising anticancer activity of a lichen, Parmelia sulcata Taylor, against breast cancer cell lines and genotoxic effect on human lymphocytes》 in 2015. The article was appeared in 《Cytotechnology》. They have made some progress in their research.Application In Synthesis of Methyl 2,4-dihydroxy-3,6-dimethylbenzoate The article mentions the following:

Plants are still to be explored for new anti-cancer compounds because overall success in cancer treatment is still not satisfactory. As a new possible source for such compounds, the lichens are recently taking a great attention. We, therefore, explored both the genotoxic and anti-growth properties of lichen species Parmelia sulcata Taylor. The chem. composition of P. sulcata was analyzed with comprehensive gas chromatog.-time of flight mass spectrometry. Anti-growth effect was tested in human breast cancer cell lines (MCF-7 and MDA-MB-231) by the MTT and ATP viability assays, while the genotoxic activity was studied by assays for micronucleus, chromosomal aberration and DNA fragmentation in human lymphocytes culture. Cell death modes (apoptosis/necrosis) were morphol. assessed. P. sulcata inhibited the growth in a dose-dependent manner up to a dose of 100 μg/mL and induced caspase-independent apoptosis. It also showed genotoxic activity at doses (>125 μg/mL) higher than that required for apoptosis. These results suggest that P. sulcata may induce caspase-independent apoptotic cell death at lower doses, while it may be genotoxic at relatively higher doses.Methyl 2,4-dihydroxy-3,6-dimethylbenzoate (cas: 4707-47-5) were involved in the experimental procedure.

Methyl 2,4-dihydroxy-3,6-dimethylbenzoate(4707-47-5) is used in biological study as role of androgens in inducing distinct response of epithelial-mesenchymal transition factors in human prostate cancer cells.Application In Synthesis of Methyl 2,4-dihydroxy-3,6-dimethylbenzoate

Reference:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Yeong, Siew Ping;Chan, Yen San;Law, Ming Chiat;Ling, Jordy Kim Ung published 《Improving cold flow properties of palm fatty acid distillate biodiesel through vacuum distillation》 in 2022. The article was appeared in 《Journal of Bioresources and Bioproducts》. They have made some progress in their research.SDS of cas: 112-62-9 The article mentions the following:

Palm fatty acid distillate (PFAD), a byproduct of refining process of crude palm oil can be used as a potential feedstock for biodiesel production However, the application of palm oil-based biodiesel is often hinder by its poor cold flow properties (CFP). Biodiesel fuel with poor CFP may crystallize and result in clogging of fuel lines, filters and injectors that cause engine operability problems. For that, a vacuum distillation method was designed and its feasibility and efficiency in improving the CFP was examined A total of 13.60wt% of total saturated fatty acid Me esters were successfully removed from the PFAD biodiesel, resulting in the improvement of the cloud point (CP), cold filter plugging point (CFPP) and pour point (PP) of PFAD biodiesel from 20°C, 19°C, and 15°C to 13°C, 11°C, and 9°C, resp. It is remarkable that the improved CFPP satisfied the requirements for grade C summer biodiesel for temperate climates in EN 14212 standard Addnl., Sarin (U_FAME) empirical correlation was evaluated and it was found to have a good prediction of CFP for PFAD biodiesel, with lower than 2°C deviation.Methyl oleate (cas: 112-62-9) were involved in the experimental procedure.

Methyl oleate(cas: 112-62-9) is a fatty acid methyl ester resulting from the formal condensation of the carboxy group of oleic acid with methanol.SDS of cas: 112-62-9 Methyl oleate(cas: 112-62-9) is an intermediate for detergents, emulsifiers, wetting agents, stabilizers, textile treatments, plasticizers for duplicating inks, rubbers, waxes etc.

Reference:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics