Xiang, Ming;Zhou, Chao;Yang, Xiu-Long;Chen, Bin;Tung, Chen-Ho;Wu, Li-Zhu published 《Visible Light-Catalyzed Benzylic C-H Bond Chlorination by a Combination of Organic Dye (Acr+-Mes) and N-Chlorosuccinimide》 in 2020. The article was appeared in 《Journal of Organic Chemistry》. They have made some progress in their research.Formula: C9H10O2 The article mentions the following:
By combining “N-chlorosuccinimide (NCS)” as the safe chlorine source with “Acr+-Mes” as the photocatalyst, we successfully achieved benzylic C-H bond chlorination under visible light irradiation Furthermore, benzylic chlorides could be converted to benzylic ethers smoothly in a one-pot manner by adding sodium methoxide. This mild and scalable chlorination method worked effectively for diverse toluene derivatives, especially for electron-deficient substrates. Careful mechanistic studies supported that NCS provided a hydrogen abstractor “N-centered succinimidyl radical,” which was responsible for the cleavage of the benzylic C-H bond, relying on the reducing ability of Acr•-Mes.Methyl 3-methylbenzoate (cas: 99-36-5) were involved in the experimental procedure.
Methyl 3-methylbenzoate (cas: 99-36-5) is a common ester.Esters are widespread in nature and are widely used in industry. In nature, fats are in general triesters derived from glycerol and fatty acids.Formula: C9H10O2 Esters are responsible for the aroma of many fruits, including apples, durians, pears, bananas, pineapples, and strawberries.
Reference:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics