Palinko, Istvan;Szabo, Pal Tamas;Torok, Bela;Kele, Zoltan;Kapocsi, Iren published 《Fragmentation of cyclobutane derivatives upon electron impact: transformation pathways elucidated by mass spectrometric methods and semiempirical quantum chemical calculations》 in 1998. The article was appeared in 《Rapid Communications in Mass Spectrometry》. They have made some progress in their research.Related Products of 3779-29-1 The article mentions the following:
The fragmentation behavior of cyclobutane derivatives (carboxylic acids, esters, cyclobutanediols, silyl ethers of the hydroxy compounds) was first studied by the GC/MS method under electron-impact (EI) ionization. Then, in order to establish the sequence of transformations, MS/MS, and in situ deuteration as well as accurate mass measurements, were performed. Anal. of these measurements revealed characteristic transformation pathways: (1) the substituents were easily cleaved; (2) in most cases the cyclobutane ring was opened with the rupture of C-C bonds opposite to each other; (3) upon ring opening, the most substituted ring C-C bond was cleaved 1st and preferentially; and (4) primary fragmentation was followed by secondary reactions including further cleavage of the ions as well as rearrangements. Sym. ring scission was observed for cyclobutanediols and their silyl ethers, providing only 1 primary fragment with m/z half that of the mol. weight This type of fragmentation was consistent with semiempirical AM1 calculations And Diethyl cyclobutane-1,1-dicarboxylate (cas: 3779-29-1) was used in the research process.
Diethyl cyclobutane-1,1-dicarboxylate (cas:3779-29-1
) is a solid catalyst that can be used in the synthesis of alkylating agents. It is used in the manufacture of cyclopropyl ketones and has been shown to exhibit anticancer properties.
Reference:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics