Stupak, Michal;Goodall, Ian;Tomaniova, Monika;Pulkrabova, Jana;Hajslova, Jana published 《A novel approach to assess the quality and authenticity of Scotch Whisky based on gas chromatography coupled to high resolution mass spectrometry》 in 2018. The article was appeared in 《Analytica Chimica Acta》. They have made some progress in their research.COA of Formula: C10H12O2 The article mentions the following:
Whisky is one of the most popular spirit drinks in the world. Unfortunately, this highly valued commodity is vulnerable to fraud. To detect fraudulent practices and document quality parameters, a number of laboratory tests based on various principles including chromatog. and spectroscopy have been developed. In most cases, the anal. methods are based on targeted screening strategies. Non-targeted screening (metabolomics fingerprinting) of (semi)volatile substances was used in our study. Following the pre-concentration of these compounds, either by solid phase microextraction (SPME) or by Et acetate extraction, gas chromatog. (GC) coupled to tandem mass spectrometry (Q-TOF mass analyzer) was employed. Unsupervised principal component anal. (PCA) and supervised partial least squares discriminant anal. (PLS-DA) were used for evaluation of data obtained by anal. of a unique set of 171 authentic whisky samples provided by the Scotch Whisky Research Institute. Very good separation of malt whiskies according to the type of cask in which they were matured (bourbon vs. bourbon and wine) was achieved, and significant ‘markers’ for bourbon and wine cask maturation, such as N-(3-methylbutyl) acetamide and 5-oxooxolane-2-carboxylic acid, were identified. Subsequently, the unique sample set was used to construct a statistical model for distinguishing malt and blended whiskies. In the final phase, 20 fake samples were analyzed and the data processed in the same way. Some differences could be observed in the (semi)volatile profiles of authentic and fake samples. Employing the statistical model developed by PLS-DA for this purpose, marker compounds that pos. distinguish fake samples were identified. To complete the study, the researchers used 1-Phenylethyl acetate (cas: 93-92-5) .
1-Phenylethyl acetate(cas:93-92-5) is a carboxylic ester. COA of Formula: C10H12O2 It may be prepared by acetylation of methyl phenyl carbinol; from 1-bromoethylbenzene and silver acetate in acetic acid; from benzaldehyde by reacting with magnesium methyl bromide and subsequent acetylation.
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