The preparation of ester heterocycles mostly uses heteroatoms as nucleophilic sites, which are achieved by intramolecular substitution or addition reactions. Compound: Bis(2,2,6,6-tetramethyl-3,5-heptanedionato)nickel(II)( cas:14481-08-4 ) is researched.Safety of Bis(2,2,6,6-tetramethyl-3,5-heptanedionato)nickel(II).Lochmuller, C. H.; Hangac, Helen H. published the article 《Mobile phase additives vs. bonded phases for HPLC》 about this compound( cas:14481-08-4 ) in Critical Reviews in Analytical Chemistry. Keywords: mobile phase additive bonded phase HPLC; diketonate mobile phase additive HPLC. Let’s learn more about this compound (cas:14481-08-4).
Probably 90% of all small-mol. HPLC separations can be done with a hydrocarbon-bonded phase of C4, C8, or C18 length using various mobile phases. The remaining 10% of the cases are more challenging. One solution is to follow the historical path of gas-liquid chromatog. and create more bonded phases. The 2nd and more easily done is to add components to the mobile phase that interact selectively with the mols. of interest and change RPLC selectivity and retention. This paper begins with a generalized discussion of additive strategy and mechanism and then leads to a study of nonionic but coordinatively unsaturated β-diketonates as additives which serves as an example of the connection between mol. chem. and chromatog. selectivity and a review of other work done. A system of coordinatively unsaturated metal β-diketonates was studied as mobile phase additives for HPLC. Unlike previous ionic, metal dopants, these neutral complexes combine reasonable elution times, high chromatog. efficiency, and enhanced chromatog. selectivity for polar compounds in normal and reversed-phase modes. The influences of mobile-phase composition, stationary-phase substrate, and metal on solute retention behavior were examined for the metal-dipivaloylmethane additive systems.
This compound(Bis(2,2,6,6-tetramethyl-3,5-heptanedionato)nickel(II))Safety of Bis(2,2,6,6-tetramethyl-3,5-heptanedionato)nickel(II) was discussed at the molecular level, the effects of temperature and reaction time on the properties of the compound were discussed, and the optimum reaction conditions were selected.
Reference:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics