In organic chemistry, atoms other than carbon and hydrogen are generally referred to as heteroatoms. The most common heteroatoms are nitrogen, oxygen and sulfur. Now I present to you an article called Catalytic Asymmetric Synthesis of the Pentacyclic Core of (+)-Citrinadin A, published in 2021-07-02, which mentions a compound: 415918-91-1, mainly applied to cycloaddition palladium diastereoselective enantioselective lithiation addition epoxidation directing group; pentacyclic core citrinadin A, Category: esters-buliding-blocks.
The synthesis of the pentacylic core of (+)-citrinadin A is described. Our strategy harnesses the power of palladium-catalyzed trimethylenemethane chem. (Pd-TMM) to form the key spirooxindole motif in a catalytic, asym. fashion. Upon the conversion of this spirooxindole to a vinyl epoxide electrophile, the piperidine ring is directly added via a diastereoselective metalation followed by an SN2′ addition The final ring of the pentacyclic core is then formed through an intramol. SN2 displacement of the resulting activated alc.
《Catalytic Asymmetric Synthesis of the Pentacyclic Core of (+)-Citrinadin A》 provides a strategy for the preparation of materials with excellent comprehensive properties, which is conducive to broaden the application field of this compound((11bR)-N,N-Bis[(1R)-1-phenylethyl]dinaphtho[2,1-d:1′,2′-f][1,3,2]dioxaphosphepin-4-amine)Category: esters-buliding-blocks.
Reference:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics