Synthetic Route of C10H8BrN. The reaction of aromatic heterocyclic molecules with protons is called protonation. Aromatic heterocycles are more basic than benzene due to the participation of heteroatoms. Compound: 6-Bromo-8-methylquinoline, is researched, Molecular C10H8BrN, CAS is 178396-31-1, about Cp*Rh(III)-Catalyzed Regioselective C(sp3)-H Electrophilic Trifluoromethylthiolation of 8-Methylquinolines. Author is Sumit; Chandra, Devesh; Thakur, Ankita; Dhiman, Ankit Kumar; Sharma, Upendra.
Rh(III)-catalyzed regioselective trifluoromethylthiolation of unactivated C(sp3)-H bond of 8-methylquinolines with bench stable electrophilic trifluoromethylthiolating reagents via C(sp3)-H activation was explored. Various substituted 8-methylquinolines provided the products in good yields with high regioselectivity. Current reaction conditions were also applicable for the late-stage functionalization of natural mol. santonin and caffeine substituted 8-methylquinoline.
This compound(6-Bromo-8-methylquinoline)Synthetic Route of C10H8BrN was discussed at the molecular level, the effects of temperature and reaction time on the properties of the compound were discussed, and the optimum reaction conditions were selected.
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