The three-dimensional configuration of the ester heterocycle is basically the same as that of the carbocycle. Compound: 6-Bromo-8-methylquinoline(SMILESS: CC1=CC(Br)=CC2=C1N=CC=C2,cas:178396-31-1) is researched.Reference of cis-Diammine(1,1-cyclobutanedicarboxylato)platinum(II). The article 《Cobalt(III)-Catalyzed 1,4-Addition of C(sp3)-H Bonds to Maleimides》 in relation to this compound, is published in Synlett. Let’s take a look at the latest research on this compound (cas:178396-31-1).
In this manuscript, an efficient and atom-economic protocol for synthesis of addition products I (R = H, 7-OCH3, 5-Cl, etc.; R1 = Me, Et, Bn, 4-FC6H4, etc.) via alkylation reactions of 8-methylquinolines II with maleimides such as N-methylmaleimide, N-phenylmaleimide, N-benzylmaleimide, etc. is presented. The reaction exhibits exceptional reactivity, satisfactory yields, excellent chemo- and regioselectivity, and tolerates a variety of functional groups.
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Reference:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics