Epoxy compounds usually have stronger nucleophilic ability, because the alkyl group on the oxygen atom makes the bond angle smaller, which makes the lone pair of electrons react more dissimilarly with the electron-deficient system. Compound: (R)-5-Benzyl-2,2,3-trimethylimidazolidin-4-one hydrochloride, is researched, Molecular C13H19ClN2O, CAS is 323196-43-6, about Thiourea-catalyzed Diels-Alder reaction of a naphthoquinone monoketal dienophile.SDS of cas: 323196-43-6.
A variety of organocatalysts were screened for the catalysis of the naphthoquinone monoketal Diels-Alder reaction. Schreiner’s thiourea catalyst 10 and Jacobson’s thiourea catalyst 12 facilitate the cycloaddition of the sterically hindered naphthoquinone monoketal dienophile with diene. The use of thiourea catalysis allowed for the first time the highly selective synthesis of the exo-product Ethyl4-((tert-butyldimethylsilyl)oxy)-5,8-dimethoxy-2-methyl-10-oxo-4,4a,9a,10-tetrahydro-l/7-spiro[anthracene- 9,2′-[1,3]dioxolane]-9a-carboxylate in up to 63% yield. In this reaction a new quaternary center was built. The so formed cycloaddition product Ethyl4-((tert-butyldimethylsilyl)oxy)-5,8-dimethoxy-2-methyl-10-oxo-4,4a,9a,10-tetrahydro-l/7-spiro[anthracene- 9,2′-[1,3]dioxolane]-9a-carboxylate represents the ABC tricycle of beticolin 0(1) and is also a valuable model substrate for the total synthesis of related natural products.
In some applications, this compound(323196-43-6)SDS of cas: 323196-43-6 is unique.If you want to know more details about this compound, you can contact with the author or consult more relevant literature.
Reference:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics