Heterocyclic compounds can be divided into two categories: alicyclic heterocycles and aromatic heterocycles. Compounds whose heterocycles in the molecular skeleton cannot reflect aromaticity are called alicyclic heterocyclic compounds. Compound: 178396-31-1, is researched, Molecular C10H8BrN, about Rh-Catalyzed Direct Amination of Unactivated C(sp3)-H bond with Anthranils Under Mild Conditions, the main research direction is rhodium catalyzed amination carbon hydrogen bond methylquinoline anthranil; C−H activation; amination; anthranils; heterocycles; rhodium.Reference of 6-Bromo-8-methylquinoline.
C-N bond formation is of great significance due to the ubiquity of nitrogen-containing compounds Here, a mild and efficient RhIII-catalyzed C(sp3)-H aryl amination reaction is reported. Anthranil is employed as the nitrogen source with 100 % atom efficiency. This C-H amination reaction exhibits broad substrate scope without using any external oxidants. Mechanistic studies including rhodacycle intermediates, H-D exchange, kinetic isotope effect (KIE) experiments, and in situ IR are presented. Thus, e.g., Rh/Ag-catalyzed amination of 8-methylquinoline with anthranil (I) in presence of PivOH additive afforded II (95%).
As far as I know, this compound(178396-31-1)Reference of 6-Bromo-8-methylquinoline can be applied in many ways, which is helpful for the development of experiments. Therefore many people are doing relevant researches.
Reference:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics