I found the field of Pharmacology & Pharmacy; Chemistry very interesting. Saw the article Synthesis of N ‘-propylhydrazide analogs of hydroxamic inhibitors of histone deacetylases (HDACs) and evaluation of their impact on activities of HDACs and replication of hepatitis C virus (HCV) published in 2019.0. Category: esters-buliding-blocks, Reprint Addresses Kozlov, MV (corresponding author), Russian Acad Sci, Engelhardt Inst Mol Biol, Vavilova 32, Moscow 119991, Russia.. The CAS is 103-25-3. Through research, I have a further understanding and discovery of Methyl 3-phenylpropionate
N’-Propylhydrazide analogs of hydroxamic inhibitors of histone deacetylases (HDACs), including tubastatin A, vorinostat and belinostat, were synthesized. All prepared compounds inhibited HDAC1/2/3, but not HDAC6, except for one hydrazide analog of HDAC4/5/7 inhibitor that was completely inactive. A novel 4-substituted derivative of N’-propylbenzohydrazide with extremely high anti-HCV activity was discovered.
Welcome to talk about 103-25-3, If you have any questions, you can contact Kozlov, MV; Konduktorov, KA; Shcherbakova, AS; Kochetkov, SN or send Email.. Category: esters-buliding-blocks
Reference:
Patent; SANOFI; US2011/294788; (2011); A1;,
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics