Adding a certain compound to certain chemical reactions, such as: 2967-93-3, name is Methyl 2-fluoro-5-methylbenzoate, belongs to esters-buliding-blocks compound, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 2967-93-3, Recommanded Product: 2967-93-3
The 2-fluoro-5-methyl benzoic acid methyl ester (100 mg, 0 . 60mmol), NBS (112 mg, 0 . 63mmol), AIBN (60 mg, 0 . 36mmol) is added in the reaction bottle, by adding CCl4(5 ml), Ar atmosphere reflow 3h, raw material a small amount of residual, reducing pressure and evaporating solvent, adding anhydrous ethyl ether (10 ml), vacuum filtration, filtrate turns on lathe does, column chromatography, to obtain 20 mg of white solid, yield 13.5%.
In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, Methyl 2-fluoro-5-methylbenzoate, other downstream synthetic routes, hurry up and to see.
Reference:
Patent; Institute Of Materia Medica Chinese Academy Of Medical Sciences; Xu, Bailing; Chen, Xiaoguang; Yao, Haiping; Ji, Ming; Jin, Jing; Zhou, Jie; Wang, Ke; Zhao, Dalong; (55 pag.)CN105461697; (2016); A;,
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics