Researchers who often do experiments know that organic synthesis is a process of preparing more complex target molecules from simple raw materials through one or more chemical reactions. Generally, it requires fewer steps, and cheap raw materials. 54535-22-7, name is Diethyl 2-((phenylamino)methylene)malonate, A new synthetic method of this compound is introduced below., COA of Formula: C14H17NO4
General procedure: Anilinomethylenemalonates 8a-c (3 g, 10.83 mmol) were refluxed for 30 min in diphenyl ether (30 mL), leading to crude oxoquinolines 9a-c which were recrystallized from dimethylformamide [20,21,26,27].
The synthetic route of 54535-22-7 has been constantly updated, and we look forward to future research findings.
Reference:
Article; Forezi, Luana Da S. M.; Tolentino, Nathalia M. C.; De Souza, Alessandra M. T.; Castro, Helena C.; Montenegro, Raquel C.; Dantas, Rafael F.; Oliveira, Maria E. I. M.; Silva Jr., Floriano P.; Barreto, Leilane H.; Burbano, Rommel M. R.; Abrahim-Vieira, Barbara; De Oliveira, Riethe; Ferreira, Vitor F.; Cunha, Anna C.; Boechat, Fernanda Da C. S.; De Souza, Maria Cecilia B. V.; Molecules; vol. 19; 5; (2014); p. 6651 – 6670;,
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