Application of 56741-34-5, In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 56741-34-5, name is Methyl 5-amino-2-fluorobenzoate belongs to esters-buliding-blocks compound, it is a common compound, a new synthetic route is introduced below.
(3) Methyl 5-amino-2-fluorobenzoate (50 g) and. 23.4 g of pyridine were dissolved in 300 ml of ethyl acetate, then 37 g of methanesulfonyl chloride was added thereto with ice-cooling and stirring and the mixture was made to react at room temperature for 3 hours. The reaction mixture was washed with water, dried, evaporated and the crystals separated out therefrom were filtered to give 72 g of methyl 2-fluoro-5-methanesulfonylaminobenzoate, m.p. 135-137 C. NMR spectra (CDCl3) delta: 3.02 (3 H, s), 3.96 (3 H, s), 6.9-7.9 (3 H, m).
The synthetic route of Methyl 5-amino-2-fluorobenzoate has been constantly updated, and we look forward to future research findings.
Reference:
Patent; Nippon Shinyaku Co. Ltd.; US5360822; (1994); A;,
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics