Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 32122-09-1, name is Ethyl 2-(benzyloxy)acetate, This compound has unique chemical properties. The synthetic route is as follows., Formula: C11H14O3
Sodium (7.13 g, 0.31 mol) was added to 500 mL of toluene. Then ethyl formate (22.9 g, 0.31 mol) and Compound 10b (60 g, 0.31 mol) were added dropwise to the above solution at a temperature of below 30 C. The reaction mixture was stirred at room temperature overnight. The solvent was concentrated, and the resulting residue was dissolved in 300 mL of ethanol, and then guanidine hydrochloride (29.45 g, 0.31 mol) was added thereto. The reaction was heated to reflux overnight. The solvent was concentrated and 100 mL of water was added to the residue, which was adjusted with 1N HCl to pH=2. The insoluble solid was collected and dried to obtain Compound 10c (30 g, Yield 44%). MS [M+1]+ 219.1.
Chemical properties determine the actual use. Each compound has specific chemical properties and uses. We look forward to more synthetic routes in the future to expand reaction routes of 32122-09-1.
Reference:
Patent; ZHEJIANG HISUN PHARMACEUTICAL CO., LTD.; Ding, Yili; Yang, Xuan; Yan, Qingyan; Bai, Hua; Cai, Lifeng; Smith, Kenneth; Chai, Jian; US2014/378488; (2014); A1;,
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