Electric Literature of 502764-52-5, As we all know, there are many different methods for the synthesis of a compound, and people can choose the synthesis method that suits their own laboratory according to the actual situation. 502764-52-5 name is Diethyl dithieno[3,2-b:2′,3′-d]thiophene-2,6-dicarboxylate, This compound is widely used in many fields, so it is necessary to find a new synthetic route. The downstream synthesis method of this compound is introduced below.
152.0 g (0.446 mol) of the compound represented by the formula 3-c obtained from the above reaction formula 17 and 2.3 L of tetrahydrofuran were added to a 5 L round bottom flask, and then 95.5 g (2,277 mol) of lithium hydroxide was dissolved in 2.3 L of water, The reaction mixture was stirred for 30 minutes and then refluxed for 6 hours. After the temperature was lowered to room temperature, 3 L of 1 N hydrochloric acid was poured, and the solid was filtered, washed with methanol and dried to obtain 112.0 g (88.2%) of the compound represented by the formula 3-d.
At the same time, in my other blogs, there are other synthetic methods of this type of compound, Diethyl dithieno[3,2-b:2′,3′-d]thiophene-2,6-dicarboxylate, and friends who are interested can also refer to it.
Reference:
Patent; SFC Ltd.; Che Jong-tae; Jeong Seong-uk; Park Seok-bae; Kang Yeong-jin; Ryu Yeon-gwon; (45 pag.)KR101791161; (2017); B1;,
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