Related Products of 344-14-9, In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 344-14-9, name is Dimethyl 2-fluoromalonate belongs to esters-buliding-blocks compound, it is a common compound, a new synthetic route is introduced below.
163 mg (2 mmol) of ethylamine hydrochloride, 1.50 g (10 mmol) of dimethyl fluoromalonate, 212 mg (2 mmol) of sodium carbonate and 10 ml of ethanol were added to the reactor,The reaction was stirred at 50 C for 10 hours.Filtration, evaporation of ethanol, the remaining mixture was directly separated by column chromatography,310 mg of methyl alpha- (N-ethyl) carbamoyrifluoroacetate was obtained in a yield95%.
In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, Dimethyl 2-fluoromalonate, other downstream synthetic routes, hurry up and to see.
Reference:
Patent; Xi’an Modern Chemical Institute; Wang Lun; Lin Shuangzheng; Li Bingbo; Wang Yuemei; Yang Cuifeng; Wu Zongkai; Wei Tianqi; (5 pag.)CN104496737; (2017); B;,
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics