Electric Literature of 711-01-3, In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 711-01-3, name is Methyl adamantane-1-carboxylate belongs to esters-buliding-blocks compound, it is a common compound, a new synthetic route is introduced below.
A suspension of Lithium Aluminium Hydride (LAH) (6.41 g, 168 mmol) in THF (250 mL) was cooled to 0 C and methyl adamantane-l-carboxylate (21.8 g, 1 12 mmol) in 50 mL of THF was added slowly at 0 C for 30 minutes. After complete addition, the reaction mixture was stirred at room temperature (RT) for 45 minutes. EtOAc (100 mL) was added slowly at 0 C followed by slow addition of water (20 mL) at 0 C. Reaction mixture was filtered and filtrate was dried over anhydrous sodium sulphate, solvent was distilled out and dried to afford the pure product (17 g, 91% yield).
The synthetic route of Methyl adamantane-1-carboxylate has been constantly updated, and we look forward to future research findings.
Reference:
Patent; ORCHID RESEARCH LABORATORIES LTD.; RAJAGOPAL, Sridharan; THANGAPAZHAM, Selvakumar; PAUL-SATYASEELA, Maneesh; BALASUBRAMANIAN, Gopalan; SHAKTI SINGH, Solanki; KUPPUSAMY, Bharathimohan; KACHHADIA, Virendra; CHENNIAPPAN, Vinoth Kumar; GANESAN, Karthikeyan; NARAYANAN, Shridhar; WO2011/58582; (2011); A1;,
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