Reference of 18595-18-1, Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 18595-18-1, name is Methyl 3-amino-4-methylbenzoate, This compound has unique chemical properties. The synthetic route is as follows.
5-Amino-2-bromo-4-methyl-benzoic acid methyl ester (69B): Following a similar procedure reported in J. Med. Chem. 1999, 42, 3701, 5-amino-2-bromo-4-methyl-benzoic acid methyl ester was prepared from methyl 3-amino-4-methylbenzoate in 77% yield. 1H-NMR (500 MHz, CDCl3).7.34 (s, 1H), 7.16 (s, 1H), 3.90 (s, 3H), 3.74 (br s, 2H), 2.19 (s, 3H).
The chemical industry reduces the impact on the environment during synthesis Methyl 3-amino-4-methylbenzoate. I believe this compound will play a more active role in future production and life.
Reference:
Patent; Bhisetti, Govinda R.; Saunders, Jeffrey O.; Murcko, Mark A.; Lepre, Christopher A.; Britt, Shawn D.; Come, Jon H.; Deininger, David D.; Wang, Tianshang; US2003/95958; (2003); A1;,
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