In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 79669-50-4, name is methyl 5-bromo-2-methyl-benzoate belongs to esters-buliding-blocks compound, it is a common compound, a new synthetic route is introduced below. SDS of cas: 79669-50-4
b) 2.8 g (12.2 mmol) of 5-bromo-2-methylbenzoate was dissolved in 19 mL of CCI4 and then NBS (2.6 g, 14.7 mmol) and benzoyl peroxide (0.28 g, 0.9 mmol) were added. The resulting yellow mixture was heated to 80 5C and stirred at that temperature overnight.The solid was removed by filtration and washed with DCM. The yellow filtrate was concentrated and purified by column chromatography over silica gel eluting with hex/EtAcO 95:5 then 9:1 to yield methyl 5-bromo-2-(bromomethyl)benzoate.
The synthetic route of 79669-50-4 has been constantly updated, and we look forward to future research findings.
Reference:
Patent; LABORATORIOS DEL DR. ESTEVE, S.A.; DRACONIS PHARMA, S.L.; ALMIRALL, S.A.; TORRENS JOVER, Andoni; MERCE VIDAL, Ramon; CALDENTEY FRONTERA, Francesc Xavier; RODRIGUEZ GARRIDO, Antonio, David; CARCELLER GONZALEZ, Elena; SALAS SOLANA, Jordi; WO2013/37960; (2013); A1;,
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