Adding a certain compound to certain chemical reactions, such as: 6942-37-6, name is Methyl 5-amino-2-bromobenzoate, belongs to esters-buliding-blocks compound, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 6942-37-6, Safety of Methyl 5-amino-2-bromobenzoate
To a cooled (5 C.) solution of 48 (4.46 g, 19.4 mmol), pyridine (8 mL, 7.6 g, 97 mmol) in DCM (90 mL) was added dropwise over a period of 20 min a solution of methanesulfonyl chloride (1.65 ml, 2.43 g, 21.3 mmol) in DCM (10 mL). The reaction mixture was stirred at RT overnight and then poured into aq. 1N HCl solution. The resulting solution was extracted with EtOAc, washed with brine, dried (MgSO4), filtered and concentrated to afford 5.7 g (95%) of 50.
In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, Methyl 5-amino-2-bromobenzoate, other downstream synthetic routes, hurry up and to see.
Reference:
Patent; Chin, Elbert; Li, Jim; Lui, Albert Sui-Ting; Talamas, Francisco Xavier; US2010/297073; (2010); A1;,
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics