Reference of 13380-85-3, Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 13380-85-3, name is Methyl 4-(hydroxymethyl)cyclohexanecarboxylate, This compound has unique chemical properties. The synthetic route is as follows.
In a nitrogen atmosphere, 7.4 g of the compound represented by the formula (I-12), 4.1 g of pyridine and 35 mL of dichloromethane were put into a reactor. With cooling with ice, 5.4 g of methanesulfonyl chloride was dropwise added thereto, and stirred at room temperature for 3 hours. This was poured into water, and washed sequentially with 5% hydrochloric acid and salt water. Purification through column chromatography (silica gel, hexane/ethyl acetate) and recrystallization (acetone/hexane) gave 7.5 g of the compound represented by the formula (I-1-3).
The chemical industry reduces the impact on the environment during synthesis Methyl 4-(hydroxymethyl)cyclohexanecarboxylate. I believe this compound will play a more active role in future production and life.
Reference:
Patent; DIC Corporation; Horiguchi, Masahiro; Mamiya, Junichi; Aoki, Yoshio; (99 pag.)US2018/312481; (2018); A1;,
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