Adding a certain compound to certain chemical reactions, such as: 10259-22-0, name is Ethyl 3-methoxybenzoate, belongs to esters-buliding-blocks compound, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 10259-22-0, Recommanded Product: Ethyl 3-methoxybenzoate
b) The hydrazone from a) (3.55 g), was dissolved in tetrahydrofuran (80 ml) and cooled to 0 C. under nitrogen while a solution of n-butyl-lithium (28.8 ml of a 2.5M solution in hexane) was added. The mixture was stirred at 0 C. for 30 minutes and then ethyl 3-methoxybenzoate (2.16 g) was added and the mixture was stirred at 0 C. for 20 minutes. 3M Hydrochloric acid (80 ml) was added and the mixture was boiled under reflux for 1 hour. The organic layer was separated and the aqueous layer was neutralized with sodium bicarbonate and extracted with ether to give an oil which is purified by flash column chromatography using 30-40% ethyl acetate in petroleum ether, b.p. 60-80 C. as the mobile phase to give 3-(3-methoxyphenyl)-1,4-dihydroindeno[1,2-c]pyrazole, m.p. 172-174 C.
In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, Ethyl 3-methoxybenzoate, other downstream synthetic routes, hurry up and to see.
Reference:
Patent; BASF Aktiengesellschaft; US6451834; (2002); B1;,
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics