In the chemical reaction process, reaction time, type of solvent, can easily affect the result of the reaction, thereby determining the yield and properties of the reaction product. An updated downstream synthesis route of 2033-24-1 as follows. Formula: C6H8O4
A solution of 2,2-dimethyl-1,3-dioxane-4,6-dione (10.0g, 69.4mmol) disolved in trimethoxymethane (40mL, 366mmol) was refluxed at 110C for 3 hours.Then the reaction mixture was cooled to room temperatue and yellow crystalformed, the crystal was filtered out, washed with petroleum ether and dried in the air to give the titled compound as a light yellow crystaline solid (7.5g,59%). 1H NMR (400 MHz, Chloroform-d) delta 8.15 (s, 1H), 4.27 (s, 3H), 1.72(s, 6H).
According to the analysis of related databases, 2033-24-1, the application of this compound in the production field has become more and more popular.
Reference:
Article; Cheng, Yu; Shen, Jian; Peng, Run-Ze; Wang, Gui-Feng; Zuo, Jian-Ping; Long, Ya-Qiu; Bioorganic and Medicinal Chemistry Letters; vol. 26; 12; (2016); p. 2900 – 2906;,
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics