In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 31600-43-8, name is Methyl 2-(benzyloxy)acetate belongs to esters-buliding-blocks compound, it is a common compound, a new synthetic route is introduced below. Formula: C10H12O3
A mixture of 70 (2.75 g, 15.3 mmol) in methanol (50 mL) and hydrazine hydrate (65% in water, 2.3 g, 30 mmol) was heated under reflux for 3 h. The reaction mixture was concentrated under reduced pressure and the residue was diluted with benzene. The solvent was evaporated and the crude product was further dried under high vacuum (6 h) to give 71 (2.75 g), as a light yellow waxy material, which was used in the next step without further purification.1H NMR (500 MHz5 CDCl3) delta 7.72 (br s, IH5 NH), 7.39-7.29 (m, 5H)5 4.56 (s5 2H), 4.07 (s, 2H)5 3.82 (br s, 2H5 NH2).
The synthetic route of 31600-43-8 has been constantly updated, and we look forward to future research findings.
Reference:
Patent; UNIVERSITY OF CONNECTICUT; WO2008/13963; (2008); A2;,
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