Related Products of 52273-79-7, In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 52273-79-7, name is Ethyl 2-(3-aminophenyl)acetate belongs to esters-buliding-blocks compound, it is a common compound, a new synthetic route is introduced below.
EXAMPLE 6 N-(3-Ethoxycarbonylmethylphenyl)-L-glutamine: Compound (6) Following the procedure described in (a) of Example 1, 11.14 g (0.03 mole) of N-carbobenzoxy-L-glutamic acid alpha-benzyl ester was reacted with 4.96 g (0.03 mole) of ethyl m-aminophenylacetate to give 12.95 g (81% yield) of an intermediate. The intermediate was dissolved in 500 ml of tetrahydrofuran, 200 ml of ethanol and 100 ml of water. To the solution was added 0.3 g of palladium black and the mixture was subjected to hydrogenation at atmospheric pressure to give 6.58 g (89% yield) of N-(3-ethoxycarbonylmethylphenyl)-L-glutamine, m.p. 175.5-176.2 C. [alpha]D25 =+26.4 (c=1 2 N HCl)
The synthetic route of Ethyl 2-(3-aminophenyl)acetate has been constantly updated, and we look forward to future research findings.
Reference:
Patent; Mitsubishi Chemical Industries Ltd.; Nippon Shinyaku Co., Ltd.; US4439448; (1984); A;,
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