Reference of 4341-76-8, In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 4341-76-8, name is Ethyl 2-butynoate belongs to esters-buliding-blocks compound, it is a common compound, a new synthetic route is introduced below.
General procedure: A mixture of 2-aminopyridine (0.1mmol), alkynoate (0.1mmol) and AgSO3CF3 (30mol%) in chlorobenzene (0.8mL) was stirred at 120C for 24h. After the reaction was finished, water (5mL) was added and the solution was extracted with ethyl acetate (3×5mL), the combined extract was dried with anhydrous MgSO4. Solvent was removed, and the residue was separated by column chromatography to give the pure sample.
The synthetic route of Ethyl 2-butynoate has been constantly updated, and we look forward to future research findings.
Reference:
Article; Chen, Zhengwang; Wen, Yuelu; Ding, Hao; Luo, Guotian; Ye, Min; Liu, Liangxian; Xue, Jun; Tetrahedron Letters; vol. 58; 1; (2017); p. 13 – 16;,
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics