Synthetic Route of 26759-46-6, In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 26759-46-6, name is Methyl 2-amino-4,5-dimethoxybenzoate belongs to esters-buliding-blocks compound, it is a common compound, a new synthetic route is introduced below.
In a 100 mL three-necked flask were added 1.5 g (6.2 mmol) of methyl 6-amino-3,4_-dimethoxybenzoate, 3 mL (75.5 mmol) of formamide, 3 mL (32.77 mmol) Oxygen Phosphorus and 25 mL of toluene were mixed and heated to reflux. TLC was carried out for 5 h and the reaction was completed. The mixture was taken out to obtain a brown solid. After adding water, the pH value was neutralized with ammonia water. A precipitate of yellowish brown color was precipitated. : EpsilonAlpha = 5: 1, V / V) to obtain a white flocculent solid 1.2 g, yield 78.7%, mp: 184-1860C.
The synthetic route of Methyl 2-amino-4,5-dimethoxybenzoate has been constantly updated, and we look forward to future research findings.
Reference:
Patent; Guizhou University; Yang Song; Zhang Dongyang; Hu Deyu; Xue Wei; Chen Ling; Liu Bin; Zhou Lei; Li Zhenxing; Wu Zhibing; (20 pag.)CN105037279; (2017); B;,
Ester – Wikipedia,
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