Discovery of 581065-95-4

Synthetic Route of 581065-95-4, A common heterocyclic compound, 581065-95-4, name is tert-Butyl 1-amino-3,6,9,12-tetraoxapentadecan-15-oate, molecular formula is C15H31NO6, its traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route.

Synthetic Route of 581065-95-4, A common heterocyclic compound, 581065-95-4, name is tert-Butyl 1-amino-3,6,9,12-tetraoxapentadecan-15-oate, molecular formula is C15H31NO6, its traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route.

(4) 50g of the amino end product obtained in step (3) was added to 100ml of 3M hydrochloric acid,The temperature was raised to 60 C and stirred for 8h.The reaction is over,Adjust PH neutral,Then spin dry,Suction filtration,The filtrate was dried over anhydrous sodium sulfate,Spin dry,35 g of pure product was obtained.NMR data are as follows:

The synthetic route of 581065-95-4 has been constantly updated, and we look forward to future research findings.

Reference:
Patent; Hunan Huateng Pharmaceutical Co., Ltd.; Deng Zeping; Li Hu; Cheng Jia; (8 pag.)CN107235848; (2017); A;,
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