Electric Literature of 27492-84-8, The chemical industry reduces the impact on the environment during synthesis 27492-84-8, name is Methyl 4-amino-2-methoxybenzoate, I believe this compound will play a more active role in future production and life.
Iodine monochloride (0.54mL, 10.5mmol)Add to methyl 4-amino-2-methoxybenzoate (1.8 g, 10 mmol)Stirring was continued for 1 hour in the methanol solution. The reaction solution is poured into water,Extracted with ethyl acetate (3×50 mL), washed with saturated brineFilter, spin dry petroleum ether / ethyl acetate (3/1)The compound 68D (2.7 g, 90percent yield) was isolated and purified.
In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, Methyl 4-amino-2-methoxybenzoate, other downstream synthetic routes, hurry up and to see.
Reference:
Patent; Jiangsu Xiansheng Pharmaceutical Co., Ltd.; Chen Huanming; Liang Bo; Cao Wenjie; Zhang Guiping; Zhao Zhongqiang; Jiang Zhaojian; Zuo Gaolei; Xu Wanmei; Gong Hongju; Zhang Peng; Wang Jianghuai; Li Qingsong; Gao Chunhua; (79 pag.)CN104045552; (2019); B;,
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics