Reference of 2439-35-2, These common heterocyclic compound, 2439-35-2, name is 2-(Dimethylamino)ethyl acrylate, its traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route.
700 g of ADAMQUAT BZ 80 are charged to a reactor with a capacity of one litre operating according to the perfectly stirred reactor technology and are brought to 38 C. with stirring and while bubbling in air. Subsequently, the ADAME (stabilized with 800 ppm of HQME), the water and the benzyl chloride are introduced simultaneously at targeted respective throughputs of 75.7 g/h (0.529 mol/h), 31.5 g/h and 65.65 g/h (0.518 mol/h) respectively, i.e. an ADAME/benzyl chloride molar ratio of 1.02 and a benzyl chloride/water ratio by weight of 2.084. [0029] The withdrawal throughput of the finished product by overflowing is 171.7 g/h, i.e. an overall residence time of 4 hours. [0030] After an operating time arbitrarily set at 6 h, i.e. 1.5 residence time, the product is analysed by HPLC. It exhibits the following characteristics: [TABLE-US-00001] HPLC analysis Content (ppm) Acrylic acid 3 418 Benzyl chloride <10 Benzyl alcohol 72
The synthetic route of 2439-35-2 has been constantly updated, and we look forward to future research findings.
Reference:
Patent; Riondel, Alain; Herbst, Gilles; Tretjak, Serge; US2004/24242; (2004); A1;,
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