Related Products of 6279-86-3, The chemical industry reduces the impact on the environment during synthesis 6279-86-3, name is Triethyl methanetricarboxylate, I believe this compound will play a more active role in future production and life.
p-Methoxyaniline (123 mg, 1 mmol) was dissolved in dimethylformamide (1 ml).;Then, triethyl methanetricarboxylate (232 mg, 1 mmol) was added.;The mixture was heated for six hours at 170-190 C. The reaction was cooled to rt and treated with ethanol, filtered and washed with ethanol to yield 8 as a yellow solid (143 mg, 58%); mp 308-310 C; 1H NMR (500 MHz, DMSO-d6) delta 3.79 (s, 3H), 3.86 (s, 3H), 7.01 (d, J = 8.9 Hz, 2H), 7.40 (br s, 3H), 7.59 (d, J = 8.9 Hz, 2H), 12.01 (s, 1H), 12.63 (s, 1H), 16.67 (s, 1H); 13C NMR (125.7 MHz, DMSO-d6) delta 55.09, 55.38, 96.39, 104.22, 114.13, 114.51, 117.33, 122.13, 123.65, 129.58, 133.11, 154.53, 156.26, 161.98, 168.39, 171.37; Anal. for C18H16N2O5: Calcd C, 63.52; H, 4.74; N, 8.23. Found C, 63.66; H, 5.00; N, 8.09.
In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, Triethyl methanetricarboxylate, other downstream synthetic routes, hurry up and to see.
Reference:
Article; Sabbah, Dima A.; Simms, Neka A.; Wang, Wang; Dong, Yuxiang; Ezell, Edward L.; Brattain, Michael G.; Vennerstrom, Jonathan L.; Zhong, Haizhen A.; Bioorganic and Medicinal Chemistry; vol. 20; 24; (2012); p. 7175 – 7183;,
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics