Related Products of 18595-14-7, These common heterocyclic compound, 18595-14-7, name is Methyl 4-amino-3-methylbenzoate, its traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route.
A mixture of compound 1 (429 mg, 0.0026 mol) and NBS (0.7 g, 0.0039 mol) in DCM was stirred at r.t. for 3 h. The mixture was concentrated to a residue, which was purified by Prep-TLC to obtain compound 2 (522 mg, 83%) as a light yellow solid
The synthetic route of 18595-14-7 has been constantly updated, and we look forward to future research findings.
Reference:
Patent; van Duzer, John H.; Mazitschek, Ralph; US2014/128391; (2014); A1;,
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