Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 251458-15-8, name is Methyl 2-(3-bromophenyl)-2-methylpropanoate, This compound has unique chemical properties. The synthetic route is as follows., Recommanded Product: Methyl 2-(3-bromophenyl)-2-methylpropanoate
A mixture of compound 21 b (319 mg, 0.7 mmol), methyl 2-(3-bromophenyl)-2-methyl- propanoate (203 mg, 0.8 mmol), Pd2(dba)3 (34 mg, 0.1 mmol), X-phos (86 mg, 0.2 mmol) and Cs2C03 (585 mg, 1.8 mmol) in toluene/.e/t-BuOH (30 mlJ5 mL) was heated to 110C overnight under N2. The mixture was cooled, filtered, concentrated and purified by FCC (PE:EA = 10:1) to give compound 21 as a yellow oil.
According to the analysis of related databases, 251458-15-8, the application of this compound in the production field has become more and more popular.
Reference:
Patent; PHENEX-FXR GMBH; GEGE, Christian; BIRKEL, Manfred; HAMBRUCH, Eva; DEUSCHLE, Ulrich; KREMOSER, Claus; (133 pag.)WO2018/188795; (2018); A1;,
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